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Article

Abbosh, C; Birkbak, NJ; Wilson, GA; Jamal-Hanjani, M; Constantin, T; Salari, R; Le Quesne, J; ... Dessimoz, C; + view all (2017) Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution. Nature , 545 pp. 446-451. 10.1038/nature22364. Green open access
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Abraham, BJ; Hnisz, D; Weintraub, AS; Kwiatkowski, N; Li, CH; Li, Z; Weichert-Leahey, N; ... Young, RA; + view all (2017) Small genomic insertions form enhancers that misregulate oncogenes. Nature Communications , 8 , Article 14385. 10.1038/ncomms14385. Green open access
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Abrol, E; Groszmann, M; Pitman, A; Hough, R; Taylor, RM; Aref-Adib, G; (2017) Exploring the digital technology preferences of teenagers and young adults (TYA) with cancer and survivors: a cross-sectional service evaluation questionnaire. Journal of Cancer Survivorship , 11 (6) pp. 670-682. 10.1007/s11764-017-0618-z. Green open access
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Afaq, A; Fraioli, F; Sidhu, H; Wan, S; Punwani, S; Chen, S-H; Akin, O; ... Kayani, I; + view all (2017) Comparison of PET/MRI With PET/CT in the Evaluation of Disease Status in Lymphoma. Clinical Nuclear Medicine , 42 (1) e1-e7. 10.1097/RLU.0000000000001344. Green open access
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Ali, A; Gale, RE; Shakoori, AR; (2017) Detection of FLT3/TKD and IDH1 Mutations in Pakistani Acute Myeloid Leukemia Patients by Denaturing HPLC. Journal of Cellular Biochemistry , 118 (5) pp. 1174-1181. 10.1002/jcb.25761. Green open access
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Ansari, T; Lange, P; Southgate, A; Greco, K; Carvalho, C; Partington, L; Bullock, A; ... Birchall, MA; + view all (2017) Stem Cell-Based Tissue-Engineered Laryngeal Replacement. Stem Cells Translational Medicine , 6 (2) pp. 677-687. 10.5966/sctm.2016-0130. Green open access
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Arends, M; Biegstraaten, M; Hughes, DA; Mehta, A; Elliott, PM; Oder, D; Watkinson, OT; ... Hollak, CEM; + view all (2017) Retrospective study of long-term outcomes of enzyme replacement therapy in Fabry disease: Analysis of prognostic factors. PLoS One , 12 (8) , Article e0182379. 10.1371/journal.pone.0182379. Green open access
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Arends, M; Körver, S; Hughes, DA; Mehta, A; Hollak, CEM; Biegstraaten, M; (2017) Phenotype, disease severity and pain are major determinants of quality of life in Fabry disease: results from a large multicenter cohort study. J Inherit Metab Dis 10.1007/s10545-017-0095-6. (In press). Green open access
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Artim-Esen, B; Smoktunowicz, N; McDonnell, T; Ripoll, VM; Pericleous, C; Mackie, I; Robinson, E; ... Giles, I; + view all (2017) Factor Xa Mediates Calcium Flux in Endothelial Cells and is Potentiated by Igg From Patients With Lupus and/or Antiphospholipid Syndrome. Scientific Reports , 7 (1) , Article 10788. 10.1038/s41598-017-11315-9. Green open access
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Banerjee, G; Wilson, D; Ambler, G; Osei-Bonsu Appiah, K; Shakeshaft, C; Lunawat, S; Cohen, H; ... CROMIS-2 Collaborators; + view all (2017) Cognitive Impairment Before Intracerebral Hemorrhage Is Associated With Cerebral Amyloid Angiopathy. Stroke , 49 pp. 40-45. 10.1161/STROKEAHA.117.019409. Green open access
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Belmatoug, N; Di Rocco, M; Fraga, C; Giraldo, P; Hughes, D; Lukina, E; Maison-Blanche, P; ... Cox, TM; + view all (2017) Management and monitoring recommendations for the use of eliglustat in adults with type 1 Gaucher disease in Europe. [Review]. European Journal of Internal Medicine , 37 pp. 25-32. 10.1016/j.ejim.2016.07.011. Green open access
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Benjamin, ER; Della Valle, MC; Wu, X; Katz, E; Pruthi, F; Bond, S; Bronfin, B; ... Lockhart, DJ; + view all (2017) The validation of pharmacogenetics for the identification of Fabry patients to be treated with migalastat. Genetics in Medicine , 19 (4) pp. 430-438. 10.1038/gim.2016.122. Green open access
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Berlato, C; Khan, MN; Schioppa, T; Thompson, R; Maniati, E; Montfort, A; Jangani, M; ... Balkwill, FR; + view all (2017) A CCR4 antagonist reverses the tumor-promoting microenvironment of renal cancer. Journal of Clinical Investigation , 127 (3) pp. 801-813. 10.1172/JCI82976. Green open access
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Bharucha, T; Rutherford, A; Skeoch, S; Alavi, A; Brown, M; Galloway, J; FDG-PET/CT in fever of unknown origin working group; (2017) Diagnostic yield of FDG-PET/CT in fever of unknown origin: a systematic review, meta-analysis, and Delphi exercise. Clinical Radiology , 72 (9) pp. 764-771. 10.1016/j.crad.2017.04.014. Green open access
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Bird, S; Hadjimichael, E; Mehta, A; Ramaswami, U; Hughes, D; (2017) Fabry disease and incidence of cancer. Orphanet Journal of Rare Diseases , 12 (1) , Article 150. 10.1186/s13023-017-0701-6. Green open access
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Boto, C; Quartin, E; Cai, Y; Martin-Lorenzo, A; Garcia Cenador, MB; Pinto, S; Gupta, R; ... Ferreira, L; + view all (2017) Prolonged intracellular accumulation of light-inducible nanoparticles in leukemia cells allows their remote activation. Nature Communications , 8 , Article 15204. 10.1038/ncomms15204. Green open access
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Butler, CR; Hynds, RE; Crowley, C; Gowers, KH; Partington, L; Hamilton, NJ; Carvalho, C; ... Janes, SM; + view all (2017) Vacuum-assisted decellularization: an accelerated protocol to generate tissue-engineered human tracheal scaffolds. Biomaterials , 124 pp. 95-105. 10.1016/j.biomaterials.2017.02.001. Green open access
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Byrne, BJ; Geberhiwot, T; Barshop, BA; Barohn, R; Hughes, D; Bratkovic, D; Desnuelle, C; ... Walsh, L; + view all (2017) A study on the safety and efficacy of reveglucosidase alfa in patients with late-onset Pompe disease. Orphanet Journal of Rare Diseases , 12 , Article 144. 10.1186/s13023-017-0693-2. Green open access
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Cavenagh, J; Oakervee, H; Baetiong-Caguioa, P; Davies, F; Gharibo, M; Rabin, N; Kurman, M; ... Yong, K; + view all (2017) A phase I/II study of KW-2478, an Hsp90 inhibitor, in combination with bortezomib in patients with relapsed/refractory multiple myeloma. British Journal of Cancer , 117 (9) pp. 1295-1302. 10.1038/bjc.2017.302. Green open access
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Chandran, S; Watkins, J; Abdul‐Aziz, A; Shafat, M; Calvert, PA; Bowles, KM; Flather, MD; ... Ryding, AD; + view all (2017) Inflammatory Differences in Plaque Erosion and Rupture in Patients With ST‐Segment Elevation Myocardial Infarction. Journal of the American Heart Association , 6 (5) , Article e005868. 10.1161/JAHA.117.005868. Green open access
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Chin, M; Sive, JI; Allen, C; Roddie, C; Chavda, SJ; Smith, D; Blombery, P; ... Yong, KL; + view all (2017) Prevalence and timing of TP53 mutations in del(17p) myeloma and effect on survival. Blood Cancer Journal , 7 , Article e610. 10.1038/bcj.2017.76. Green open access
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Cox, S; Hurt, C; Grenader, T; Mukherjee, S; Bridgewater, J; Crosby, T; (2017) The prognostic value of derived neutrophil to lymphocyte ratio in oesophageal cancer treated with definitive chemoradiotherapy. Radiotherapy and Oncology , 125 (1) pp. 154-159. 10.1016/j.radonc.2017.08.023. Green open access
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Crosby, T; Hurt, CN; Falk, S; Gollins, S; Staffurth, J; Ray, R; Bridgewater, JA; ... Mukherjee, S; + view all (2017) Long-term results and recurrence patterns from SCOPE-1: a phase II/III randomised trial of definitive chemoradiotherapy +/- cetuximab in oesophageal cancer. British Journal of Cancer , 116 pp. 709-716. 10.1038/bjc.2017.21. Green open access
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Davis, BA; Allard, S; Qureshi, A; Porter, JB; Pancham, S; Win, N; Cho, G; ... British Society for Haematology, .; + view all (2017) Guidelines on red cell transfusion in sickle cell disease Part II: indications for transfusion. British Journal of Haematology , 176 (2) pp. 192-209. 10.1111/bjh.14383. Green open access
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Dias, J; Axelband, F; Lara, LS; Muzi-Filho, H; Vieyra, A; (2017) Is angiotensin-(3–4) (Val-Tyr), the shortest angiotensin II-derived peptide, opening new vistas on the renin–angiotensin system? Journal of the Renin-Angiotensin-Aldosterone System , 18 (1) 10.1177/1470320316689338. Green open access
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Domogala, A; Blundell, M; Thrasher, A; Lowdell, MW; Madrigal, JA; Saudemont, A; (2017) Natural killer cells differentiated in vitro from cord blood CD34(+) cells are more advantageous for use as an immunotherapy than peripheral blood and cord blood natural killer cells. Cytotherapy , 19 (6) pp. 710-720. 10.1016/j.jcyt.2017.03.068. Green open access
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Elliott, MJ; Butler, CR; Varanou-Jenkins, A; Partington, L; Carvalho, C; Samuel, E; Crowley, C; ... Birchall, MA; + view all (2017) Tracheal Replacement Therapy with a Stem Cell-Seeded Graft: Lessons from Compassionate Use Application of a GMP-Compliant Tissue-Engineered Medicine. Stem Cells Translational Medicine , 6 (6) pp. 1458-1464. 10.1002/sctm.16-0443. Green open access
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Eyre, TA; Phillips, EH; Linton, KM; Kassam, S; Gibb, A; Allibone, S; Radford, J; ... Collins, GP; + view all (2017) Results of a multicentre UK-wide retrospective study evaluating the efficacy of brentuximab vedotin in relapsed, refractory classical Hodgkin lymphoma in the transplant naive setting. British Journal of Haematology , 179 (3) pp. 471-479. 10.1111/bjh.14898. Green open access
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Furness, CL; Smith, L; Morris, E; Brocklehurst, C; Daly, S; Hough, RE; (2017) Cancer Patient Experience in the Teenage Young Adult Population-Key Issues and Trends Over Time: An Analysis of the United Kingdom National Cancer Patient Experience Surveys 2010-2014. Journal of Adolescent and Young Adult Oncology , 6 (3) pp. 450-458. 10.1089/jayao.2016.0058. Green open access
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Galleu, A; Riffo-Vasquez, Y; Trento, C; Lomas, C; Dolcetti, L; Cheung, TS; von Bonin, M; ... Dazzi, F; + view all (2017) Apoptosis in mesenchymal stromal cells induces in vivo recipient-mediated immunomodulation. Science Translational Medicine , 9 (416) , Article eaam7828. 10.1126/scitranslmed.aam7828. Green open access
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Ganeshan, B; Miles, KA; Babikir, S; Shortman, R; Afaq, A; Ardeshna, KM; Groves, AM; (2017) CT-based texture analysis potentially provides prognostic information complementary to interim fdg-pet for patients with hodgkin's and aggressive non-hodgkin's lymphomas. European Radiology , 27 (3) pp. 1012-1020. 10.1007/s00330-016-4470-8. Green open access
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Garbowski, MW; Evans, P; Vlachodimitropoulou, E; Hider, R; Porter, JB; (2017) Residual erythropoiesis protects against myocardial hemosiderosis in transfusion-dependent thalassemia by lowering labile plasma iron via transient generation of apotransferrin. Haematologica , 102 pp. 1640-1649. 10.3324/haematol.2017.170605. Green open access
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Gardiner, C; Kohama, K; Patel, I; Lane, P; Dwyer, S; Machin, SJ; Mackie, IJ; (2017) A performance evaluation of a novel human recombinant tissue factor prothrombin time reagent (Revohem (TM) PT). International Journal of Laboratory Hematology , 39 (5) pp. 532-538. 10.1111/ijlh.12691. Green open access
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Ghorani, E; Kaur, B; Fisher, RA; Short, D; Joneborg, U; Carlson, JW; Akarca, A; ... Seckl, MJ; + view all (2017) Pembrolizumab is effective for drugresistant gestational trophoblastic neoplasia. The Lancet , 390 (10110) pp. 2343-2345. 10.1016/S0140-6736(17)32894-5. Green open access
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Gleeson, M; Counsell, N; Cunningham, D; Chadwick, N; Lawrie, A; Hawkes, EA; McMillan, A; ... Linch, D; + view all (2017) Central nervous system relapse of diffuse large B-cell lymphoma in the rituximab era: results of the UK NCRI R-CHOP-14 versus 21 trial. Annals of Oncology , 28 (10) pp. 2511-2516. 10.1093/annonc/mdx353. Green open access
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Goel, A; Raghupathy, V; Amirtharaj, GJ; Chapla, A; Venkatraman, A; Ramakrishna, B; Ramachandran, A; ... Eapen, CE; + view all (2017) ADAMTS13 missense variants associated with defective activity and secretion of ADAMTS13 in a patient with non-cirrhotic portal hypertension. Indian Journal of Gastroenterology , 36 (5) pp. 380-389. 10.1007/s12664-017-0786-9. Green open access
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Gohil, SH; Paredes-Moscosso, SR; Harrasser, M; Vezzalini, M; Scarpa, A; Morris, E; Davidoff, AM; ... Della Peruta, M; + view all (2017) An ROR1 bi-specific T-cell engager provides effective targeting and cytotoxicity against a range of solid tumors. OncoImmunology , 6 (7) , Article e1326437. 10.1080/2162402X.2017.1326437. Green open access
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Goodship, THJ; Pinto, F; Weston-Davies, WH; Silva, J; Nishimura, J-I; Nunn, MA; Mackie, I; ... Veys, P; + view all (2017) Use of the complement inhibitor Coversin to treat HSCT-associated TMA. Blood Advances , 1 (16) pp. 1254-1258. 10.1182/bloodadvances.2016002832. Green open access
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Green, K; Pearce, K; Sellar, RS; Jardine, L; Nicolson, PLR; Nagra, S; Bigley, V; ... Collin, M; + view all (2017) Impact of Alemtuzumab Scheduling on Graft-versus-Host Disease after Unrelated Donor Fludarabine and Melphalan Allografts. Biology of Blood and Marrow Transplantation , 23 (5) pp. 805-812. 10.1016/j.bbmt.2017.02.007. Green open access
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Griffiths, PD; Rothwell, E; Raza, M; Wilmore, S; Doyle, T; Harber, M; O'Beirne, J; ... Emery, VC; + view all (2017) Correction: Randomized Controlled Trials to Define Viral Load Thresholds for Cytomegalovirus Pre-Emptive Therapy. [Corrigendum]. PLOS ONo , 12 (9) , Article e0185298. 10.1371/journal.pone.0185298. Green open access
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Hachani, R; Birchall, MA; Lowdell, MW; Kasparis, G; Tung, LD; Manshian, BB; Soenen, SJ; ... Thanh, NTK; + view all (2017) Assessing cell-nanoparticle interactions by high content imaging of biocompatible iron oxide nanoparticles as potential contrast agents for magnetic resonance imaging. Scientific Reports , 7 (1) , Article 7850. 10.1038/s41598-017-08092-w. Green open access
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Hartwig, T; Montinaro, A; von Karstedt, S; Sevko, A; Surinova, S; Chakravarthy, A; Taraborrelli, L; ... Walczak, H; + view all (2017) The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2. Molecular Cell , 65 (4) pp. 730-742. 10.1016/j.molcel.2017.01.021. Green open access
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Hough, R; Sandhu, S; Khan, M; Moran, A; Feltbower, R; Stiller, C; Stevens, MCG; ... McCabe, MG; + view all (2017) Are survival and mortality rates associated with recruitment to clinical trials in teenage and young adult patients with acute lymphoblastic leukaemia? A retrospective observational analysis in England. BMJ Open , 7 (10) , Article e017052. 10.1136/bmjopen-2017-017052. Green open access
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Hughes, D; Giugliani, R; Guffon, N; Jones, SA; Mengel, KE; Parini, R; Matousek, R; ... Quartel, A; + view all (2017) Clinical outcomes in a subpopulation of adults with Morquio A syndrome: results from a long-term extension study of elosulfase alfa. Orphanet Journal of Rare Diseases , 12 , Article 98. 10.1186/s13023-017-0634-0. Green open access
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Hughes, DA; Nicholls, K; Shankar, SP; Sunder-Plassmann, G; Koeller, D; Nedd, K; Vockley, G; ... Feldt-Rasmussen, U; + view all (2017) Oral pharmacological chaperone migalastat compared with enzyme replacement therapy in Fabry disease: 18-month results from the randomised phase III ATTRACT study. Journal of Medical Genetics , 54 (4) pp. 288-296. 10.1136/jmedgenet-2016-104178. Green open access
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Irshad, S; Flores-Borja, F; Lawler, K; Monypenny, J; Evans, R; Male, V; Gordon, P; ... Ng, T; + view all (2017) RORγt+ innate lymphoid cells promote lymph node metastasis of breast cancers. Cancer Research , 77 (5) pp. 1083-1096. 10.1158/0008-5472.CAN-16-0598. Green open access
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Jackson, LH; Vlachodimitropoulou, E; Shangaris, P; Roberts, TA; Ryan, TM; Campbell-Washburn, AE; David, AL; ... Stuckey, DJ; + view all (2017) Non-invasive MRI biomarkers for the early assessment of iron overload in a humanized mouse model of β-thalassemia. Scientific Reports , 7 , Article 43439. 10.1038/srep43439. Green open access
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Jamal-Hanjani, M; Wilson, GA; McGranahan, N; Birkbak, NJ; Watkins, TBK; Veeriah, S; Shafi, S; ... Swanton, C; + view all (2017) Tracking the Evolution of Non-Small-Cell Lung Cancer. New England Journal of Medicine , 376 (22) pp. 2109-2121. 10.1056/NEJMoa1616288. Green open access
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Joshi, K; Chain, BM; Peggs, KS; Quezada, SA; (2017) The "Achilles Heel" of Cancer and Its Implications for the Development of Novel Immunotherapeutic Strategies. Cold Spring Harbor Perspectives in Medicine 10.1101/cshperspect.a027086. (In press). Green open access
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Kantarjian, H; Stein, A; Goekbuget, N; Fielding, AK; Schuh, AC; Ribera, J-M; Wei, A; ... Topp, MS; + view all (2017) Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia. New England Journal of Medicine , 376 (9) pp. 836-847. 10.1056/NEJMoa1609783. Green open access
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Kato, I; Nishinaka, Y; Nakamura, M; Akarca, AU; Niwa, A; Ozawa, H; Yoshida, K; ... Enver, T; + view all (2017) Hypoxic adaptation of leukemic cells infiltrating the CNS affords a therapeutic strategy targeting VEGFA. Blood , 129 (23) pp. 3126-3129. 10.1182/blood-2016-06-721712. Green open access
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Kirk, P; Sheppard, M; Carpenter, J-P; Anderson, L; He, T; St Pierre, T; Galanello, R; ... Pennell, DJ; + view all (2017) Post-mortem study of the association between cardiac iron and fibrosis in transfusion dependent anaemia. Journal of Cardiovascular Magnetic Resonance , 19 (1) , Article 36. 10.1186/s12968-017-0349-3. Green open access
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Knapper, S; Russell, N; Gilkes, A; Hills, RK; Gale, RE; Cavenagh, JD; Jones, G; ... Burnett, AK; + view all (2017) A randomised assessment of adding the kinase inhibitor lestaurtinib to 1st-line chemotherapy for FLT3-mutated AML. Blood , 129 (9) pp. 1143-1154. 10.1182/blood-2016-07-730648. Green open access
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Kozor, R; Nordin, S; Treibel, TA; Rosmini, S; Castelletti, S; Fontana, M; Captur, G; ... Moon, JC; + view all (2017) Insight into hypertrophied hearts: a cardiovascular magnetic resonance study of papillary muscle mass and T1 mapping. European Heart Journal - Cardiovascular Imaging , 18 (9) pp. 1034-1040. 10.1093/ehjci/jew187. Green open access
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Kühnl, A; Cunningham, D; Counsell, N; Hawkes, EA; Qian, W; Smith, P; Chadwick, N; ... Linch, D; + view all (2017) Outcome of Elderly Patients with Diffuse Large B-cell Lymphoma Treated with R-CHOP: Results from the UK NCRI R-CHOP14v21 trial with combined analysis of molecular characteristics with the DSHNHL RICOVER-60 trial. Annals of Oncology , 28 (7) pp. 1540-1546. 10.1093/annonc/mdx128. Green open access
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Latifoltojar, A; Hall-Craggs, M; Bainbridge, A; Rabin, N; Popat, R; Rismani, A; D'Sa, S; ... Punwani, S; + view all (2017) Whole-body MRI quantitative biomarkers are associated significantly with treatment response in patients with newly diagnosed symptomatic multiple myeloma following bortezomib induction. European Radiology 10.1007/s00330-017-4907-8. (In press). Green open access
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Latifoltojar, A; Hall-Craggs, M; Rabin, N; Popat, R; Bainbridge, A; Dikaios, N; Sokolska, M; ... Yong, K; + view all (2017) Whole body magnetic resonance imaging in newly diagnosed multiple myeloma: early changes in lesional signal fat fraction predict disease response. British Journal of Haematology , 176 (2) pp. 222-233. 10.1111/bjh.14401. Green open access
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Lee, E; Milan, A; Urbani, L; De Coppi, P; Lowdell, MW; (2017) Decellularized material as scaffolds for tissue engineering studies in long gap esophageal atresia. Expert Opinion on Biological Therapy , 17 (5) pp. 573-584. 10.1080/14712598.2017.1308482. Green open access
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Lee, KCL; Baker, L; Mallett, S; Riddell, A; Chowdary, P; Alibhai, H; Chang, Y-M; ... Agarwal, B; + view all (2017) Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs. Scientific Reports , 7 (1) , Article 9347. 10.1038/s41598-017-09508-3. Green open access
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Lee, L; Draper, B; Chaplin, N; Philip, B; Chin, M; Galas-Filipowicz, D; Onuoha, S; ... Pule, M; + view all (2017) An APRIL based chimeric antigen receptor for dual targeting of BCMA and TACI in Multiple Myeloma. Blood , 2017 (5) , Article 781351. 10.1182/blood-2017-05-781351. Green open access
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Li, Z; Abraham, BJ; Berezovskaya, A; Farah, N; Liu, Y; Leon, T; Fielding, A; ... Look, AT; + view all (2017) APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL. Leukemia 10.1038/leu.2017.75. Green open access
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Linch, M; Goh, G; Hiley, C; Shanmugabavan, Y; McGranahan, N; Rowan, A; Wong, YNS; ... Swanton, C; + view all (2017) Intratumoural evolutionary landscape of high-risk prostate cancer: the PROGENY study of genomic and immune parameters. Annals of Oncology , 28 (10) pp. 2472-2480. 10.1093/annonc/mdx355. Green open access
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Llombart, V; Alejandro Trejo, S; Bronsoms, S; Morancho, A; Ma, F; Faura, J; Garcia-Berrocoso, T; ... Montaner, J; + view all (2017) Profiling and identification of new proteins involved in brain ischemia using MALDI-imaging-mass-spectrometry. Journal of Proteomics , 152 pp. 243-253. 10.1016/j.jprot.2016.11.014. Green open access
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Lowdell, MW; Thomas, A; (2017) The expanding role of the clinical haematologist in the new world of advanced therapy medicinal products. British Journal of Haematology , 176 (1) pp. 9-15. 10.1111/bjh.14384. Green open access
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Maccari, G; Robinson, J; Ballingall, K; Guethlein, LA; Grimholt, U; Kaufman, J; Ho, CS; ... Marsh, SG; + view all (2017) IPD-MHC 2.0: an improved inter-species database for the study of the major histocompatibility complex. Nucleic Acids Research , 45 (D1) D860-D864. 10.1093/nar/gkw1050. Green open access
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Maciocia, N; Melville, A; Cheesman, S; Sharpley, F; Ramasamy, K; Streetly, M; Jenner, M; ... Rabin, N; + view all (2017) Real-world use of pomalidomide and dexamethasone in double refractory multiple myeloma suggests benefit in renal impairment and adverse genetics: a multi-centre UK experience. British Journal of Haematology , 176 (6) pp. 908-917. 10.1111/bjh.14547. Green open access
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Maciocia, PM; Wawrzyniecka, PA; Akarca, AU; Philip, B; Ricciardelli, I; Somja, J; Onuoha, SC; ... Pule, MA; + view all (2017) Targeting T-cell receptor β-constant region for immunotherapy of T-cell malignancies. Nature Medicine , 23 (12) pp. 1416-1423. 10.1038/nm.4444. Green open access
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Marlein, CR; Zaitseva, L; Piddock, RE; Robinson, SD; Edwards, DR; Shafat, MS; Zhou, Z; ... Rushworth, SA; + view all (2017) NADPH oxidase-2 derived superoxide drives mitochondrial transfer from bone marrow stromal cells to leukemic blasts. Blood , 130 (14) pp. 1649-1660. 10.1182/blood-2017-03-772939. Green open access
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Martinelli, G; Boissel, N; Chevallier, P; Ottmann, O; Goekbuget, N; Topp, MS; Fielding, AK; ... Stein, A; + view all (2017) Complete Hematologic and Molecular Response in Adult Patients With Relapsed/Refractory Philadelphia Chromosome-Positive B-Precursor Acute Lymphoblastic Leukemia Following Treatment With Blinatumomab: Results From a Phase II, Single-Arm, Multicenter Study. Journal of Clinical Oncology , 35 (16) pp. 1795-1802. 10.1200/JCO.2016.69.3531. Green open access
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Martinez, C; Gayoso, J; Canals, C; Finel, H; Peggs, K; Dominietto, A; Castagna, L; ... Sureda, A; + view all (2017) Post-Transplantation Cyclophosphamide-Based Haploidentical Transplantation as Alternative to Matched Sibling or Unrelated Donor Transplantation for Hodgkin Lymphoma: A Registry Study of the Lymphoma Working Party of the European Society for Blood and Marrow Transplantation. Journal of Clinical Oncology , 35 (30) pp. 3425-3432. 10.1200/JCO.2017.72.6869. Green open access
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Matalonga, J; Glaria, E; Bresque, M; Escande, C; Carbó, JM; Kiefer, K; Vicente, R; ... Valledor, AF; + view all (2017) The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism. Cell Reports , 18 (5) pp. 1241-1255. 10.1016/j.celrep.2017.01.007. Green open access
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Mattar, CNZ; Gil-Farina, I; Rosales, C; Johana, N; Tan, YYW; McIntosh, J; Kaeppel, C; ... Chan, JKY; + view all (2017) In Utero Transfer of Adeno-Associated Viral Vectors Produces Long-Term Factor IX Levels in a Cynomolgus Macaque Model. Molecular Therapy , 25 (8) pp. 1843-1853. 10.1016/j.ymthe.2017.04.003. Green open access
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Maughan, EF; Hynds, RE; Proctor, TJ; Janes, SM; Elliott, M; Birchall, MA; Lowdell, MW; (2017) Autologous Cell Seeding in Tracheal Tissue Engineering. Current Stem Cell Reports , 3 (4) pp. 279-289. 10.1007/s40778-017-0108-2. Green open access
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Mavroudis, CA; Eleftheriou, D; Hong, Y; Majumder, B; Koganti, S; Sapsford, R; North, J; ... Rakhit, RD; + view all (2017) Microparticles in acute coronary syndrome. Thrombosis Research , 156 pp. 109-116. 10.1016/j.thromres.2017.06.003. Green open access
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McGranahan, N; Rosenthal, R; Hiley, CT; Rowan, AJ; Watkins, TBK; Wilson, GA; Birkbak, NJ; ... Swanton, C; + view all (2017) Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution. Cell 10.1016/j.cell.2017.10.001. (In press). Green open access
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McNamara, MG; Bridgewater, J; Lopes, A; Wasan, H; Malka, D; Jensen, LH; Okusaka, T; ... Valle, JW; + view all (2017) Systemic therapy in younger and elderly patients with advanced biliary cancer: sub-analysis of ABC-02 and twelve other prospective trials. BMC Cancer , 17 , Article 262. 10.1186/s12885-017-3266-9. Green open access
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Megias, D; Phillips, M; Clifton-Hadley, L; Harron, E; Eaton, DJ; Sanghera, P; Whitfield, G; (2017) Dose specification for hippocampal sparing whole brain radiotherapy (HS WBRT): considerations from the UK HIPPO trial QA programme. British Journal Of Radiology , 90 (1071) , Article 20160829. 10.1259/bjr.20160829. Green open access
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Mehta, A; Belmatoug, N; Bembi, B; Deegan, P; Elstein, D; Göker-Alpan, Ö; Lukina, E; ... Hughes, D; + view all (2017) Exploring the patient journey to diagnosis of Gaucher disease from the perspective of 212 patients with Gaucher disease and 16 Gaucher expert physicians. Molecular Genetics and Metabolism , 122 (3) pp. 122-129. 10.1016/j.ymgme.2017.08.002. Green open access
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Miller, PDE; de Silva, T; Skinner, R; Gilleece, M; Peniket, A; Hamblin, A; Greenfield, D; ... Snowden, JA; + view all (2017) Routine vaccination practice after adult and paediatric allogeneic haematopoietic stem cell transplant: a survey of UK NHS programmes. Bone Marrow Transplantation , 52 pp. 775-777. 10.1038/bmt.2016.362. Green open access
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Mlcochova, P; Sutherland, KA; Watters, SA; Bertoli, C; de Bruin, RAM; Rehwinkel, J; Neil, SJ; ... Gupta, RK; + view all (2017) A G1-like state allows HIV-1 to bypass SAMHD1 restriction in macrophages. The EMBO Journal , 36 (5) pp. 604-616. 10.15252/embj.201696025. Green open access
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Morris, EC; Fox, T; Chakraverty, R; Tendeiro, R; Snell, K; Rivat, C; Grace, S; ... Thrasher, AJ; + view all (2017) Gene therapy for Wiskott-Aldrich syndrome in a severely affected adult. Blood , 130 pp. 1327-1335. 10.1182/blood-2017-04-777136. Green open access
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Nathwani, AC; Davidoff, AM; Tuddenham, EGD; (2017) Advances in Gene Therapy for Haemophilia. Hum Gene Ther 10.1089/hum.2017.167. Green open access
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Nathwani, AC; Davidoff, AM; Tuddenham, EGD; (2017) Gene Therapy for Hemophilia. Hematology/Oncology Clinics of North America , 31 (5) pp. 853-868. 10.1016/j.hoc.2017.06.011. Green open access
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Ngwenya, N; Kenten, C; Jones, L; Gibson, F; Pearce, S; Flatley, M; Hough, R; ... Whelan, J; + view all (2017) Experiences and Preferences for End-of-Life Care for Young Adults with Cancer and Their Informal Carers: A Narrative Synthesis. Journal of Adolescent and Young Adult Oncology , 6 (2) pp. 200-212. 10.1089/jayao.2016.0055. Green open access
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Nienhuis, AW; Nathwani, AC; Davidoff, AM; (2017) Gene Therapy for Hemophilia. [Review]. Molecular Therapy , 25 (5) pp. 1163-1167. 10.1016/j.ymthe.2017.03.033. Green open access
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O'Connor, D; Moorman, AV; Wade, R; Hancock, J; Tan, RMR; Bartram, J; Moppett, J; ... Samarasinghe, S; + view all (2017) Use of Minimal Residual Disease Assessment to Redefine Induction Failure in Pediatric Acute Lymphoblastic Leukemia. Journal of Clinical Oncology , 35 (6) pp. 660-667. 10.1200/JCO.2016.69.6278. Green open access
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Pastores, GM; Hughes, DA; (2017) Lysosomal Storage Disorders and Malignancy. Diseases , 5 (1) 10.3390/diseases5010008. Green open access
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Porter, JB; Cappellini, MD; Kattamis, A; Viprakasit, V; Musallam, KM; Zhu, Z; Taher, AT; (2017) Iron overload across the spectrum of non-transfusion-dependent thalassaemias: role of erythropoiesis, splenectomy and transfusions. British Journal of Haematology , 176 (2) pp. 288-299. 10.1111/bjh.14373. Green open access
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Porter, JB; Elalfy, M; Taher, A; Aydinok, Y; Lee, SH; Sutcharitchan, P; El-Ali, A; ... El-Beshlawy, A; + view all (2017) Limitations of serum ferritin to predict liver iron concentration responses to deferasirox therapy in patients with transfusion-dependent thalassaemia. European Journal of Haematology , 98 (3) pp. 280-288. 10.1111/ejh.12830. Green open access
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Post, M; Cuapio, A; Osl, M; Lehmann, D; Resch, U; Davies, DM; Bilban, M; ... Hofer, E; + view all (2017) The Transcription Factor ZnF683/hOBiT regulates human NK-cell Development. Frontiers in Immunology , 8 , Article 535. 10.3389/fimmu.2017.00535. Green open access
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Pugh, G; Hough, R; Gravestock, H; Williams, K; Fisher, A; (2017) Lifestyle advice provision to teenage and young adult cancer patients: the perspective of health professionals in the UK. Support Care in Cancer , 25 (12) pp. 3823-3832. 10.1007/s00520-017-3814-5. Green open access
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Pugh, G; Hough, RE; Gravestock, HL; Jackson, SE; Fisher, A; (2017) The Health Behavior Information Needs and Preferences of Teenage and Young Adult Cancer Survivors. Journal of Adolescent and Young Adult Oncology , 6 (2) pp. 318-326. 10.1089/jayao.2016.0089. Green open access
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Pugh, S; Thiébaut, R; Bridgewater, J; Grisoni, ML; Moutasim, K; Rousseau, F; Thomas, GJ; ... Laurent-Puig, P; + view all (2017) Association between miR-31-3p expression and cetuximab efficacy in patients with KRAS wild-type metastatic colorectal cancer: A post-hoc analysis of the New EPOC trial. Oncotarget , 8 (55) pp. 93856-93866. 10.18632/oncotarget.21291. Green open access
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Qasim, W; Zhan, H; Samarasinghe, S; Adams, S; Amrolia, P; Stafford, S; Butler, K; ... Veys, P; + view all (2017) Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells. Science Translational Medicine , 9 (374) , Article eaaj2013. 10.1126/scitranslmed.aaj2013. Green open access
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Radford, J; McKay, P; Malladi, R; Johnson, R; Bloor, A; Percival, F; Sureda, A; (2017) Treatment pathways and resource use associated with recurrent Hodgkin lymphoma after autologous stem cell transplantation. Bone Marrow Transplant , 52 pp. 452-454. 10.1038/bmt.2016.244. Green open access
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Rahman, S; Magnussen, M; León, TE; Farah, N; Li, Z; Abraham, BJ; Alapi, KZ; ... Mansour, MR; + view all (2017) Activation of the LMO2 oncogene through a somatically acquired neomorphic promoter in T-cell acute lymphoblastic leukemia. Blood , 129 (24) pp. 3221-3226. 10.1182/blood-2016-09-742148. Green open access
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Robinson, J; Guethlein, LA; Cereb, N; Yang, SY; Norman, PJ; Marsh, SGE; Parham, P; (2017) Distinguishing functional polymorphism from random variation in the sequences of >10,000 HLA-A, -B and -C alleles. PLoS Genetics , 13 (6) , Article e1006862. 10.1371/journal.pgen.1006862. Green open access
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Roddie, C; Peggs, KS; (2017) Immunotherapy for transplantation-associated viral infections. Journal Of Clinical Investigation , 127 (7) pp. 2513-2522. 10.1172/JCI90599. Green open access
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Rossig, C; Pule, M; Altvater, B; Saiagh, S; Wright, G; Ghorashian, S; Clifton-Hadley, L; ... Amrolia, PJ; + view all (2017) Vaccination to improve the persistence of CD19CAR gene-modified T cells in relapsed pediatric acute lymphoblastic leukemia. Leukemia , 31 pp. 1087-1095. 10.1038/leu.2017.39. Green open access
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Russell, LJ; Jones, L; Enshaei, A; Tonin, S; Ryan, SL; Eswaran, J; Nakjang, S; ... Harrison, CJ; + view all (2017) Characterisation of the genomic landscape of CRLF2-rearranged acute lymphoblastic leukemia. Genes, Chromosomes and Cancer , 56 (5) pp. 363-372. 10.1002/gcc.22439. Green open access
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Schiffmann, R; Hughes, DA; Linthorst, GE; Ortiz, A; Svarstad, E; Warnock, DG; West, ML; (2017) Screening, diagnosis, and management of patients with Fabry disease: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference. Kidney International , 91 (2) pp. 284-293. 10.1016/j.kint.2016.10.004. Green open access
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Schoser, B; Fong, E; Geberhiwot, T; Hughes, D; Kissel, JT; Madathil, SC; Orlikowski, D; ... Young, P; + view all (2017) Maximum inspiratory pressure as a clinically meaningful trial endpoint for neuromuscular diseases: a comprehensive review of the literature. [Review]. Orphanet Journal of Rare Diseases , 12 , Article 52. 10.1186/s13023-017-0598-0. Green open access
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Shafat, MS; Oellerich, T; Mohr, S; Robinson, SD; Edwards, DR; Marlein, CR; Piddock, RE; ... Rushworth, SA; + view all (2017) Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment. Blood , 129 (10) pp. 1320-1332. 10.1182/blood-2016-08-734798. Green open access
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Shaw, BE; Mayor, NP; Szydlo, RM; Bultitude, WP; Anthias, C; Kirkland, K; Perry, J; ... Marsh, SG; + view all (2017) Recipient/donor HLA and CMV matching in recipients of T-cell-depleted unrelated donor haematopoietic cell transplants. Bone Marrow Transplant , 52 pp. 717-725. 10.1038/bmt.2016.352. Green open access
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Siddharthan, T; Grigsby, M; Miele, CH; Bernabe-Ortiz, A; Miranda, JJ; Gilman, RH; Wise, RA; ... Checkley, W; + view all (2017) Prevalence and risk factors of restrictive spirometry in a cohort of Peruvian adults. The International Journal of Tuberculosis and Lung Disease , 21 (9) pp. 1062-1068. 10.5588/ijtld.17.0101. Green open access
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Singer, R; Campbell, P; Fernandes, C; Statham, P; Hochhauser, D; Bridgewater, J; (2017) Time to endoscopic intervention in patients with upper gastrointestinal patients can be improved with pathway provision. BMC Cancer , 17 , Article 365. 10.1186/s12885-017-3335-0. Green open access
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Snowden, JA; Greenfield, DM; Bird, JM; Boland, E; Bowcock, S; Fisher, A; Low, E; ... UK Myeloma Forum (UKMF) and the British Society for Haematology, .; + view all (2017) Guidelines for screening and management of late and long-term consequences of myeloma and its treatment. British Journal of Haematology , 176 (6) pp. 888-907. 10.1111/bjh.14514. Green open access
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Taher, AT; Origa, R; Perrotta, S; Kourakli, A; Ruffo, GB; Kattamis, A; Goh, AS; ... Porter, JB; + view all (2017) New film-coated tablet formulation of deferasirox is well tolerated in patients with thalassemia or lower-risk MDS: Results of the randomized, phase II ECLIPSE study. American Journal of Hematology , 92 (5) pp. 420-428. 10.1002/ajh.24668. Green open access
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Taieb, J; Kourie, HR; Emile, J-F; Le Malicot, K; Balogoun, R; Tabernero, J; Mini, E; ... Pan-European Trials in Alimentary Tract Cancer (PETACC)-8 Invest; + view all (2017) Association of Prognostic Value of Primary Tumor Location in Stage III Colon Cancer With RAS and BRAF Mutational Status. JAMA Oncology 10.1001/jamaoncol.2017.3695. (In press).

Tailor, H; Mackie, I; Mellick, A; Machin, S; (2017) Evaluation of the Sysmex XN-550, a Novel Compact Haematology analyser from the XN-L (R) series, compared to the XN-20 system. International Journal of Laboratory Hematology , 39 (6) pp. 585-589. 10.1111/ijlh.12701. Green open access
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Taylor, SA; Mallett, S; Miles, A; Beare, S; Bhatnagar, G; Bridgewater, J; Glynne-Jones, R; ... Halligan, S; + view all (2017) Streamlining staging of lung and colorectal cancer with whole body MRI; study protocols for two multicentre, non-randomised, single-arm, prospective diagnostic accuracy studies (Streamline C and Streamline L). BMC Cancer , 17 , Article 299. 10.1186/s12885-017-3281-x. Green open access
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Tostoes, R; Dodgson, J; Weil, B; Gerontas, S; Mason, C; Veraitch, FS; (2017) A novel filtration system for point of care washing of cellular therapy products. Journal of Tissue Engineering and Regenerative Medicine , 11 (11) pp. 3157-3167. 10.1002/term.2225. Green open access
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Tuddenham, EG; (2017) Platelets are a safe way to deliver factor VIII. After 13 years of preclinical research it is now time for a clinical trial. Journal of Thrombosis and Haemostasis , 15 (1) pp. 96-97. 10.1111/jth.13545. Green open access
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Turajlic, S; Litchfield, K; Xu, H; Rosenthal, R; McGranahan, N; Reading, JL; Wong, YNS; ... Swanton, C; + view all (2017) Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis. The Lancet Oncology , 18 (8) pp. 1009-1021. 10.1016/S1470-2045(17)30516-8. Green open access
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Vargas, FA; Furness, AJS; Solomon, I; Joshi, K; Mekkaoui, L; Lesko, MH; Rota, EM; ... Quezada, SA; + view all (2017) Fc-Optimized Anti-CD25 Depletes Tumor-Infiltrating Regulatory T Cells and Synergizes with PD-1 Blockade to Eradicate Established Tumors. Immunity , 46 (4) pp. 577-586. 10.1016/j.immuni.2017.03.013. Green open access
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Vlachodimitropoulou, E; Chen, Y-L; Garbowski, M; Koonyosying, P; Psaila, B; Sola-Visner, M; Cooper, N; ... Porter, J; + view all (2017) Eltrombopag: a powerful chelator of cellular or extracellular iron(III) alone or combined with a second chelator. Blood , 130 (17) pp. 1923-1933. 10.1182/blood-2016-10-740241. Green open access
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Vos, JM; Notermans, NC; D'Sa, S; Lunn, MP; van der Pol, WL; Kraan, W; Reilly, MM; ... Minnema, MC; + view all (2017) High prevalence of the MYD88 L265P mutation in IgM anti-MAG paraprotein-associated peripheral neuropathy. [Letter]. Journal of Neurology, Neurosurgery & Psychiatry , 89 (9) pp. 1007-1009. 10.1136/jnnp-2017-316689. Green open access
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Weil, BD; Jenkins, MJ; Uddin, S; Bracewell, DG; Wellings, D; Farid, SS; Veraitch, F; (2017) An integrated experimental and economic evaluation of cell therapy affinity purification technologies. Regenerative Medicine , 12 (4) pp. 397-417. 10.2217/rme-2016-0156. Green open access
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Wong, YNS; Joshi, K; Pule, M; Peggs, KS; Swanton, C; Quezada, SA; Linch, M; (2017) Evolving adoptive cellular therapies in urological malignancies. Lancet Oncology , 18 (6) E341-E353. 10.1016/S1470-2045(17)30327-3. Green open access
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Wood, G; Grenader, T; Nash, S; Adams, R; Kaplan, R; Fisher, D; Maughan, T; (2017) Derived neutrophil to lymphocyte ratio as a prognostic factor in patients with advanced colorectal cancer according to RAS and BRAF status: a post-hoc analysis of the MRC COIN study. Anti-Cancer Drugs , 28 (5) pp. 546-550. 10.1097/CAD.0000000000000488. Green open access
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Yang, J; Milasta, S; Hu, D; AlTahan, AM; Interiano, RB; Zhou, J; Davidson, J; ... Davidoff, AM; + view all (2017) Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox. Cancer Research , 77 (17) pp. 4626-4638. 10.1158/0008-5472.CAN-16-0826. Green open access
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Proceedings paper

Efthymiou, M; Mackie, IJ; Lane, P; Erkan, D; Cohen, H; (2017) High prevalence of activated protein C resistance associated with high avidity anti-protein C antibodies in various antiphospholipid syndrome clinical phenotypes. In: (Proceedings) ISTH 2017. Green open access
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Thesis

Agliardi, Giulia; (2017) Development of a Chimeric Antigen Receptor (CAR) - based T cell therapy for glioblastoma. Doctoral thesis (Ph.D), UCL (University College London). Green open access
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De Ascensão Santos e Sousa, Pedro Miguel; (2017) A systems immunology approach to graft-versus-host disease. Doctoral thesis , UCL (University College London). Green open access
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Garbowski, MW; (2017) Molecular and clinical factors affecting myocardial iron retention in transfusional haemosiderosis. Doctoral thesis , UCL (University College London). Green open access
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Hotblack, AC; (2017) Characterising the role of dendritic cells in TCR gene therapy. Doctoral thesis , UCL (University College London). Green open access
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Kramer, AM; (2017) Delineating the impact of binding-domain affinity and kinetic properties on Chimeric Antigen Receptor T-cell function. Doctoral thesis , UCL (University College London). Green open access
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Lee, Doyoung; (2017) Investigation of mechanisms for enhancing expression of human FVIII in vitro; application to therapeutic protein production. Doctoral thesis , UCL (University College London). Green open access
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Lee, LSH; (2017) APRIL based therapeutic strategies to target BCMA and TACI in multiple myeloma. Doctoral thesis , UCL (University College London). Green open access
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Maciocia, PM; (2017) Targeting the T-cell Receptor Beta Constant Region for Investigation and Immunotherapy of T-cell Malignancies. Doctoral thesis , UCL (University College London). Green open access
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Reed, M; (2017) Characterisation of pathogenic pathways within the bone microenvironment of Gaucher Disease which contribute to bone pathology and haematological malignancy. Doctoral thesis , UCL (University College London). Green open access
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Weil, BD; (2017) Purification Of Progenitor Photoreceptors Derived From The Directed Differentiation Of Human Pluripotent Stem Cells. Doctoral thesis , UCL (University College London). Green open access
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This list was generated on Sun Oct 20 23:28:34 2024 BST.