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Number of items: 22.
Article
Abbas, SH;
Pickett, E;
Lomas, DA;
Thorburn, D;
Gooptu, B;
Hurst, JR;
Marshall, A;
(2020)
Non-invasive testing for liver pathology in alpha-1 antitrypsin deficiency.
BMJ Open Respiratory Research
, 7
(1)
, Article e000820. 10.1136/bmjresp-2020-000820.
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Day, NC;
Kumar, S;
Criner, G;
Dransfield, M;
Halpin, DMG;
Han, MK;
Jones, CE;
... Lipson, DA; + view all
(2020)
Single-inhaler triple therapy fluticasone furoate/umeclidinium/vilanterol versus fluticasone furoate/vilanterol and umeclidinium/vilanterol in patients with COPD: results on cardiovascular safety from the IMPACT trial.
Respiratory Research
, 21
, Article 139. 10.1186/s12931-020-01398-w.
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Dransfield, MT;
Crim, C;
Criner, GJ;
Day, NC;
Halpin, DMG;
Han, MK;
Jones, CE;
... Lange, P; + view all
(2020)
Risk of Exacerbation and Pneumonia with Single Inhaler Triple Versus Dual Therapy in IMPACT.
Annals of the American Thoracic Society
10.1513/AnnalsATS.202002-096OC.
(In press).
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Faull, SV;
Elliston, ELK;
Gooptu, B;
Jagger, AM;
Aldobiyan, I;
Redzej, A;
Badaoui, M;
... Lomas, DA; + view all
(2020)
The structural basis for Z α₁-antitrypsin polymerization in the liver.
Science Advances
, 6
(43)
, Article eabc1370. 10.1126/sciadv.abc1370.
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Halpin, DMG;
Criner, GJ;
Dransfield, MT;
Han, MK;
Hartley, B;
Harvey, C;
Jones, CE;
... Lipson, DA; + view all
(2020)
Triple Versus Dual Combination Therapy in Chronic Obstructive Pulmonary Disease in Asian Countries: Analysis of the IMPACT Trial.
Pulmonary Therapy
10.1007/s41030-020-00136-3.
(In press).
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Halpin, DMG;
Dransfield, MT;
Han, MK;
Jones, CE;
Kilbride, S;
Lange, P;
Lipson, DA;
... Criner, GJ; + view all
(2020)
The Effect of Exacerbation History on Outcomes in the IMPACT Trial.
European Respiratory Journal
, 55
, Article 1901921. 10.1183/13993003.01921-2019.
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Han, MK;
Criner, GJ;
Dransfield, MT;
Halpin, DMG;
Jones, CE;
Kilbride, S;
Lange, P;
... Martinez, FJ; + view all
(2020)
The Effect of ICS Withdrawal and Baseline Inhaled Treatment on Exacerbations in the IMPACT Study: A Randomized, Double-blind Multicenter Trial.
American Journal of Respiratory and Critical Care Medicine
10.1164/rccm.201912-2478OC.
(In press).
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Jagger, AM;
Waudby, CA;
Irving, JA;
Christodoulou, J;
Lomas, DA;
(2020)
High-resolution ex vivo NMR spectroscopy of human Z α1-antitrypsin.
Nature Communications
, 11
, Article 6371. 10.1038/s41467-020-20147-7.
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Kurzawa-Akanbi, M;
Keogh, M;
Tsefou, E;
Ramsay, L;
Johnson, M;
Keers, S;
Ochieng, LWSA;
... Morris, CM; + view all
(2020)
Neuropathological and biochemical investigation of Hereditary Ferritinopathy cases with ferritin light chain mutation: Prominent protein aggregation in the absence of major mitochondrial or oxidative stress.
Neuropathology and Applied Neurobiology
10.1111/nan.12634.
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Laffranchi, M;
Elliston, EL;
Miranda, E;
Perez, J;
Ronzoni, R;
Jagger, AM;
Heyer-Chauhan, N;
... Irving, JA; + view all
(2020)
Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin.
JCI Insight
, 5
(14)
, Article e135459. 10.1172/jci.insight.135459.
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Lipson, DA;
Crim, C;
Criner, GJ;
Day, NC;
Dransfield, MT;
Halpin, DMG;
Han, MK;
... Martinez, FJ; + view all
(2020)
Reduction in All-Cause Mortality with Fluticasone Furoate/Umeclidinium/Vilanterol in COPD Patients.
American Journal of Respiratory and Critical Care Medicine
10.1164/rccm.201911-2207oc.
(In press).
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Murray, MJ;
Bonilla-Medrano, NI;
Lee, QL;
Oxenford, SJ;
Angell, R;
Depledge, DP;
Reeves, MB;
(2020)
Evasion of a human cytomegalovirus entry inhibitor with potent cysteine reactivity is concomitant with the utilisation of a heparan sulfate proteoglycan independent route of entry.
Journal of Virology
10.1128/JVI.02012-19.
(In press).
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Ninou, I;
Sevastou, I;
Magkrioti, C;
Kaffe, E;
Stamatakis, G;
Thivaios, S;
Panayotou, G;
... Aidinis, V; + view all
(2020)
Genetic deletion of Autotaxin from CD11b+ cells decreases the severity of experimental autoimmune encephalomyelitis.
PLoS One
, 15
(4)
, Article e0226050. 10.1371/journal.pone.0226050.
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Roberts, M;
Sevastou, I;
Imaizumi, Y;
Mistry, K;
Talma, S;
Dey, M;
Gartlon, J;
... de Silva, R; + view all
(2020)
Pre-clinical characterisation of E2814, a high-affinity antibody targeting the microtubule-binding repeat domain of tau for passive immunotherapy in Alzheimer's disease.
Acta Neuropathologica Communications
, 8
, Article 13. 10.1186/s40478-020-0884-2.
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Ronzoni, R;
Heyer‐Chauhan, N;
Fra, A;
Pearce, AC;
Rüdiger, M;
Miranda, E;
Irving, JA;
(2020)
The molecular species responsible for α₁‐antitrypsin deficiency are suppressed by a small molecule chaperone.
The FEBS Journal
10.1111/febs.15597.
(In press).
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Sampson, D;
Yager, TD;
Fox, B;
Shallcross, L;
McHugh, L;
Seldon, T;
Rapisarda, A;
... Noursadeghi, M; + view all
(2020)
Blood transcriptomic discrimination of bacterial and viral infections in the emergency department: a multi-cohort observational validation study.
BMC Medicine
, 18
(1)
10.1186/s12916-020-01653-3.
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Singer, M;
Shipley, R;
Baker, T;
Cowell, A;
Brealey, D;
Lomas, D;
(2020)
The UCL Ventura CPAP device for COVID-19.
The Lancet Respiratory Medicine
, 8
(11)
pp. 1076-1078.
10.1016/S2213-2600(20)30422-7.
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Strnad, P;
McElvaney, NG;
Lomas, DA;
(2020)
Alpha₁-Antitrypsin Deficiency.
The New England Journal of Medicine
, 382
(15)
pp. 1443-1455.
10.1056/NEJMra1910234.
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Tabberer, M;
Jones, CE;
Kilbride, S;
Halpin, DMG;
Lomas, DA;
Pascoe, S;
Singh, D;
... Lipson, DA; + view all
(2020)
Single-Inhaler Triple Therapy and Health-Related Quality of Life in COPD: The IMPACT Study.
Advances in Therapy
10.1007/s12325-020-01409-8.
(In press).
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Turner, CT;
Gupta, RK;
Tsaliki, E;
Roe, JK;
Mondal, P;
Nyawo, GR;
Palmer, Z;
... Noursadeghi, M; + view all
(2020)
Blood transcriptional biomarkers for active pulmonary tuberculosis in a high-burden setting: a prospective, observational, diagnostic accuracy study.
The Lancet Respiratory Medicine
10.1016/S2213-2600(19)30469-2.
(In press).
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Wilson, AC;
Kumar, PL;
Lee, S;
Parker, MM;
Arora, I;
Morrow, JD;
Wouters, EFM;
... McDonald, M-LN; + view all
(2020)
Heme metabolism genes Downregulated in COPD Cachexia.
Respiratory
, 21
, Article 100. 10.1186/s12931-020-01336-w.
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Wilson, J;
Herron, D;
Nachev, P;
McNally, N;
Williams, B;
Rees, G;
(2020)
The Value of Data: Applying a Public Value Model to the English National Health Service.
JMIR - Journal of Medical Internet Research
, 22
(3)
, Article e15816. 10.2196/15816.
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